| Abstract:To investigate the genetic polymorphism of Dickkopf-1 ( DKK1) gene in yak and reveal the association between SNPs detected and growth traits,and looking for alternative auxiliary marker. This study selected 287 individuals which include five yak breeds named Maiwa,Leiwuqi ,Shenzha ,Pali and Sibu,to detect the SNPs of the DKK1 gene in yaks and its correlation with the growth traits of yak. The results showed that:there are two mutations in the DKK1 gene,each of them has three different genotypes. The χ value of g.983A→G site in SB yak was 6.324 2,which meant the site was out-off-balance of the Hardy-Weinberg equilibrium (HWE),but the rest of sites matched the balance of the HWE;the distribution of both SNPs were moderate polymorphic;the correlation analysis between different genotypes of two SNPs of DKK1 gene and body height,body length,chest bust,cannon circumference,body mass and other growth traits showed that g.983A→G site was associated with body height,body length,chest bust,and body mass,but no significant difference was detected between g.1075C→G and growth traits. |
